期刊
JOURNAL OF OLEO SCIENCE
卷 61, 期 9, 页码 515-523出版社
JAPAN OIL CHEMISTS SOC
DOI: 10.5650/jos.61.515
关键词
caffeine; capsaicin; diabetes; glucose; KK-A(gamma) mouse
资金
- National Project Regional Innovation Cluster Program (2nd stage, Sapporo Biocluster Bio-S and Hakodate Marine Biocluster)
- MEXT (Ministry of Education, Culture, Sports, Science and Tecnology, Japan)
- Grants-in-Aid for Scientific Research [23380068] Funding Source: KAKEN
The present study is aimed to measure the effect of caffeine and capsaicin on the blood glucose level of obese/diabetic model mice. The blood glucose level of KK-A(gamma) obese/diabetic mice decreased significantly after dietary supplementations with less than 0.031% caffeine and less than 0.0042% capsaicin, while both food ingredients and the combination had little effect on body weight gain and abdominal white adipose tissue (WAT) weight at this dose. The blood glucose level of the control mice was 234.4 mg/dL at 10 days after feeding and it increased to 500.6 mg/dL after 28 days, while levels after intake of caffeine, capsaicin, and both together increased from 180, 131.6, and 140 mg/dL to 183.7, 255.1, and 151.6 mg/dL, respectively. The anti-diabetic activity of caffeine and capsaicin was confirmed by a decrease in total drinking water and in the blood insulin level.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据