期刊
JOURNAL OF NEUROSURGERY-PEDIATRICS
卷 5, 期 5, 页码 507-510出版社
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/2009.12.PEDS09173
关键词
pilocytic astrocytoma; malignant transformation; optic pathway glioma; glioblastoma multiforme; radiation therapy
Optic pathway gliomas (OPGs) arise from the optic nerves, optic chiasm, and/or hypothalamus and most commonly occur in childhood. Although these tumors can be quite challenging to manage, they are typically low-grade astrocytomas histologically, most commonly pilocytic astrocytomas. The few previously reported cases of malignant degeneration of an OPG occurred after external beam radiation therapy. The authors report the first case in the English literature of an OPG that transformed from a low-grade astrocytoma, with features most consistent with a pilocytic astrocytoma, to a malignant glioma without any exposure to radiation therapy. (DOI: 10.3171/2009.12.PEDS09173)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据