期刊
JOURNAL OF NEUROSURGERY
卷 111, 期 4, 页码 874-883出版社
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/2009.2.JNS081380
关键词
cerebrospinal fluid fistula; Gamma Knife surgery; neurofibromatosis Type 2; retrosigmoidal craniotomy; rhinorrhea; vestibular schwannoma
Object. The aim of this study was to identify patients likely to develop CSF leaks after vestibular schwannoma surgery using a retrospective analysis for the identification of risk factors. Methods. Between January 2001 and December 2006, 420 patients underwent retrosigmoidal microsurgical tumor removal in a standardized procedure. Of these 420 patients, 363 underwent treatment for the first time, and 27 suffered from recurrent tumors. Twenty-six patients had bilateral tumors due to neurofibromatosis Type 2, and 4 patients had previously undergone radiosurgical treatment. An analysis was performed to examine the incidence of postoperative CSF fistulas in all 4 groups. Results. The incidence of CSF leakage was higher in the tumor recurrence group (11.1%) than in patients undergoing surgery for the first time (4.4%). There were no CSF fistulas in the neurofibromatosis Type 2 group or in patients with preoperative radiosurgical treatment. Tumor size was identified as a possible risk factor in a previous study. Conclusions. Surgery for recurrent tumors is a significant risk factor for the development of CSF leaks. (DOI: 10.3171/2009.2.JNS081380)
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