期刊
JOURNAL OF NEUROSCIENCE METHODS
卷 195, 期 2, 页码 261-269出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jneumeth.2010.11.015
关键词
EEG; ECoG; Source imaging; Functional connectivity; MATLAB; eConnectome
资金
- NIH/NIBIB [RO1 EB006433, RO1 EB007920]
We have developed a MATLAB-based toolbox, eConnectome (electrophysiological connectome), for mapping and imaging functional connectivity at both the scalp and cortical levels from the electroencephalogram (EEG), as well as from the electrocorticogram (ECoG). Graphical user interfaces were designed for interactive and intuitive use of the toolbox. Major functions of eConnectome include EEG/ECoG preprocessing, scalp spatial mapping, cortical source estimation, connectivity analysis, and visualization. Granger causality measures such as directed transfer function and adaptive directed transfer function were implemented to estimate the directional interactions of brain functional networks, over the scalp and cortical sensor spaces. Cortical current density inverse imaging was implemented using a generic realistic geometry brain-head model from scalp EEGs. Granger causality could be further estimated over the cortical source domain from the inversely reconstructed cortical source signals as derived from the scalp EEG. Users may implement other connectivity estimators in the framework of eConnectome for various applications. The toolbox package is open-source and freely available at http://econnectome.umn.edu under the GNU general public license for noncommercial and academic uses. (C) 2010 Elsevier B.V. All rights reserved.
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