期刊
JOURNAL OF NEUROSCIENCE METHODS
卷 183, 期 1, 页码 42-48出版社
ELSEVIER
DOI: 10.1016/j.jneumeth.2009.05.015
关键词
Synchronization; Epilepsy; Complex networks; Seizure prediction; Seizure prevention; Seizure detection; Focus localization
资金
- Deutsche Forschungsgemeinschaft
Epilepsy is a malfunction of the brain that affects over 50 million people worldwide. Epileptic seizures are usually characterized by an abnormal synchronized firing of neurons involved in the epileptic process. In human epilepsy the exact mechanisms underlying seizure generation are still uncertain as are mechanisms underlying seizure spreading and termination. There is now growing evidence that an improved understanding of the epileptic process can be achieved through the analysis of properties of epileptic brain networks and through the analysis of interactions in such networks. In this overview, we summarize recent methodological developments to assess synchronization phenomena in human epileptic brain networks and present findings obtained from analyses of brain electromagnetic signals recorded in epilepsy patients. (C) 2009 Elsevier B.V. All rights reserved.
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