期刊
JOURNAL OF NEUROSCIENCE
卷 32, 期 5, 页码 1867-1874出版社
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.5181-11.2012
关键词
-
资金
- Medical Research Council
- Lister prize fellowship
- Medical Research Council [G0901899, G0901307] Funding Source: researchfish
- MRC [G0901307, G0901899] Funding Source: UKRI
Mature presynaptic terminals release neurotransmitter both in response to activity and spontaneously. We found that axons of rat hippocampal neurons initially show very high levels of exclusively spontaneous release, which progressively switches over to the mature phenotype during synapse formation. These two modes of vesicle cycling derive from distinct pools throughout development and the initiation of activity-dependent release was independent of postsynaptic contacts, suggesting it is an autonomous presynaptic event.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据