期刊
JOURNAL OF NEUROSCIENCE
卷 29, 期 6, 页码 1766-1772出版社
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.5259-08.2009
关键词
verbal instruction; prefrontal cortex; conflict; fMRI; cognitive control; ACC; pre-SMA
资金
- Special Research Fund (Bijzonder Onderzoeksfond) of Ghent University.
One of the major evolutionary advances of human primates in the motor domain is their ability to use verbal instructions to guide their behavior. Despite this fundamental role of verbal information for our behavioral regulation, the functional and neural mechanisms underlying the transformation of verbal instructions into efficient behavior are still poorly understood. To gain deeper insights into the motor representation of verbal instructions, we investigated the neural circuits involved in overcoming interference from stimulus response (S-R) mappings that are merely instructed and S-R mappings that are implemented. Implemented and instructed S-R mappings revealed a partly overlapping pattern of fronto-parietal brain activity when compared with a neutral condition. However, the direct contrast revealed a clear difference with stronger activation for the implemented condition in the ACC, bilateral inferior parietal cortex, the cerebellum and the precentral sulcus. This indicates that instructed S-R mappings share some properties with implemented S-R mappings but that they are lacking the motor-related properties of implemented mappings.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据