期刊
JOURNAL OF NEUROLOGY
卷 256, 期 -, 页码 S310-S316出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00415-009-5242-z
关键词
Cell transplantation; Lewy body; Therapy; Dopaminergic
Postmortem analyses from clinical neural transplantation trials of several subjects with Parkinson's disease revealed surviving grafted dopaminergic neurons after more than a decade. A subset of these subjects displayed isolated dopaminergic neurons within the grafts that contained Lewy body-like structures. In this review, we discuss why this isolated cell damage is unlikely to affect the overall graft function and how we can use these observations to help us to understand age-related neurodegeneration and refine our future cell replacement therapies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据