期刊
JOURNAL OF NEUROIMMUNOLOGY
卷 251, 期 1-2, 页码 94-102出版社
ELSEVIER
DOI: 10.1016/j.jneuroim.2012.07.001
关键词
Autism; B cell; Immunoglobulin; Immune system
资金
- NIEHS [1P01ES11269-01]
- U.S. EPA [R829388]
- EPA [1099720, R829388] Funding Source: Federal RePORTER
Autism spectrum disorders are a heterogeneous group of behaviorally defined disorders having complex etiologies. We previously reported a direct correlation between lower plasma levels of the immunoglobulins (Ig) IgG and IgM and increased severity of behavioral symptoms in children with autism. Our current objective was to determine if these reduced plasma levels of IgG and IgM are the result of defective B cell development, activation, or function. Results suggest no differences in the B cell parameters measured, indicating that decreased Ig in autism is not a result of B cell dysfunction and other immune cells might be involved. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据