期刊
JOURNAL OF NEUROIMMUNOLOGY
卷 201, 期 -, 页码 237-244出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jneuroim.2008.07.012
关键词
Myasthenia gravis; Thymoma; VATET; Thymomectomy
We studied 197 patients with thymoma-associated myasthenia gravis (T-MG) to identify variables that can influence the natural history of the disease and the therapeutical approaches. Multivariate analysis showed that neither clinical nor pathological variables were associated with a better chance to reach complete stable remission. The video-assisted thoracoscopic extended thymectomy (VATET) was not significantly correlated with a lower chance of achieving complete stable remission compared with the classical transsternal approach (T-3b)) = 0.1090). Thymoma recurrence was not correlated with surgery by VATET or T-3b. VATET was safe and reliable for removal of thymoma. The low chance of achieving remission (9.64%) in T-MG underlines the importance of an early diagnosis as well as the need for more aggressive therapeutic strategies. (c) 2008 Elsevier B.V. All rights reserved.
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