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Florian Plattner et al.
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Formation of Tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1)
K Tanemura et al.
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G Hajishengallis et al.
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DE Kang et al.
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DD Sarbassov et al.
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Hippocampal Spatial Memory Impairments Caused by the Familial Alzheimer's Disease-Linked Presenilin 1 M146V Mutation
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Functional reconstitution of γ-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2
G Periz et al.
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L Baki et al.
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R Wang et al.
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Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2
RB Feng et al.
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XG Huang et al.
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Direct cadherin-activated cell signaling: a view from the plasma membrane
AS Yap et al.
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T Bussiere et al.
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Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory
SJ Liu et al.
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Signal transduction from N-cadherin increases Bcl-2 - Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization
NL Tran et al.
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Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: Findings from the nun study
KP Riley et al.
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Familial frontotemporal dementia associated with a novel presenilin-1 mutation
D Tang-Wai et al.
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Transglutaminase bonds in neurofibrillary tangles and paired helical filament tau early in Alzheimer's disease
SM Singer et al.
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The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
CA Grimes et al.
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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
MA Chishti et al.
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C Russ et al.
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Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex
L Baki et al.
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Dementia with prominent frontotemporal features associated with L113P presenilin 1 mutation
G Raux et al.
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