AlCl3-PROMOTED THIOCYANATION OF N-CONTAINING AROMATIC AND HETEROAROMATIC COMPOUNDS UNDER SOLVENT-FREE CONDITIONS

Aluminum chloride/Ammonium thiocyanate (AlCl3/NH4SCN) was found to be an effective system for the thiocyanation of some arylamines and indoles to afford the corresponding thiocyanated adducts at room temperature under solvent-free conditions. The efficacy of this combined reagent was also examined in the thiocyanation of pyrrole and isatin. A plausible mechanism of thiocyanation has also been suggested.