期刊
JOURNAL OF NEURAL ENGINEERING
卷 6, 期 3, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/1741-2560/6/3/035007
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资金
- Biotechnology and Biological Sciences Research Council [BB/F021127/1, F021127] Funding Source: Medline
- Medical Research Council [G9900989] Funding Source: Medline
- BBSRC [BB/F021127/1] Funding Source: UKRI
- EPSRC [EP/F029241/1] Funding Source: UKRI
- MRC [G9900989] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/F021127/1] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/F029241/1] Funding Source: researchfish
- Medical Research Council [G9900989] Funding Source: researchfish
The recent discovery that neurons call be photostimulated via genetic incorporation of artificial opsins is creating a revolution in the field of neural stimulation. In this paper we show its potential in the field of retinal prosthesis. We show that we need typically 100 mW cm(-2) in instantaneous light intensity on the neuron in order to stimulate action potentials. We also show how this can be reduced down to safe levels in order to negate thermal and photochromic damage to the eye. We also describe a gallium nitride LED light Source which is also able to generate patterns of the required intensity in order to transfer reliable images.
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