期刊
JOURNAL OF NATURAL PRODUCTS
卷 76, 期 4, 页码 750-754出版社
AMER CHEMICAL SOC
DOI: 10.1021/np300876t
关键词
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资金
- Japan Society for the Promotion of Science (JSPS) AA Scientific Platform Program
- High-Tech Research Center Project, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [S0801043]
Four new 4-hydroxy-2-pyridone alkaloids, didymellamides A-D (1-4), were isolated from the marine-derived fungus Stagonosporopsis cucurbitacearum. The structures of 1-4 were elucidated from spectroscopic data (NMR, MS, and IR), and the absolute configuration of 1 was determined by X-ray diffraction analysis. Didymellamide A (1) exhibited antifungal activity against azole-resistant Candida albicans.
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