4.7 Article

Melodinines M-U, Cytotoxic Alkaloids from Melodinus suaveolens

期刊

JOURNAL OF NATURAL PRODUCTS
卷 75, 期 2, 页码 220-224

出版社

AMER CHEMICAL SOC
DOI: 10.1021/np2009169

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资金

  1. Natural Science Foundation of China [31170334, 21072198]
  2. National Basic Research Program of China (973 Program) [2009CB522300]
  3. Chinese Academy of Sciences [KSCX2-EW-R-15]

向作者/读者索取更多资源

Nine new alkaloids, melodinines M-U (1-9), and 11 known alkaloids were isolated from Melodinus suaveolens. The new structures were elucidated by extensive NMR and mass spectroscopic analyses and comparison to known compounds. All compounds were evaluated for their cytotoxicity against five human cancer cell lines. Compounds 6, 11, and 16 showed significant cytotoxicity.

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