期刊
JOURNAL OF NATURAL PRODUCTS
卷 75, 期 1, 页码 115-118出版社
AMER CHEMICAL SOC
DOI: 10.1021/np200845f
关键词
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资金
- Ministerio de Ciencia e Innovacion [BIO2007-61745, SAF2009-08039, SAF2010-16858]
- DGUI Gobierno de Canarias [PIO42005, PUB2005/030]
Dactylomelatriol (1), obtained from the sea hare Aplysia dactylomela, is the first naturally occurring omphalane-derived sesquiterpene from the marine environment. From this species the known chamigrene and modified bisabolene sesquiterpenes 2-6 were also isolated. The structure and relative configuration of I were established by spectroscopic evidence. Its chemical structure is related to omphalic acid, the unique terrestrial-derived omphalane sesquiterpene isolated from a liverwort. A biogenetic route for this compound is proposed. The antimicrobial activities of compounds 1-6 were evaluated against a panel of microorganisms.
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