期刊
JOURNAL OF NATURAL PRODUCTS
卷 74, 期 4, 页码 670-674出版社
AMER CHEMICAL SOC
DOI: 10.1021/np100727h
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资金
- CHE
- Ministry of Education, Culture, Sports, Science and Technology, Japan
- Commission on Higher Education (CHE), Ministry of Education, Thailand
A new spirotetronate-class polyketide, maklamicin (1), was isolated from the culture extract. of an endophytic actinomycete of the genus Micromonospora. The structure and relative configuration of were elucidated by interpretation of NMR and other spectroscopic data, and the absolute configuration was determined using the Modified Mosher method: Maklamicin (1) showed strong to modest antimicrobial activity against Gram-positive bacteria.
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