4.7 Article

Chisomicines A-C, Limonoids from Chisocheton ceramicus

期刊

JOURNAL OF NATURAL PRODUCTS
卷 74, 期 5, 页码 1313-1317

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AMER CHEMICAL SOC
DOI: 10.1021/np200013g

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  1. University Malaya [PS378/2009B]
  2. CNRS (France)
  3. Ministry of Education, Culture, Sports, Science, and Technology of Japan
  4. Open Research Center

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Three new limonoids, chisomicines A-C (1-3), have been isolated from the bark of Chisocheton ceramicus. Their structures were determined by 2D NMR, CD spectroscopic methods, and X-ray analysis. Chisomicine A (1) exhibited NO production inhibitory activity in J774.1 cells stimulated by LPS dose-dependently at high cell viability.

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