期刊
JOURNAL OF NATURAL PRODUCTS
卷 74, 期 3, 页码 512-517出版社
AMER CHEMICAL SOC
DOI: 10.1021/np1006394
关键词
-
资金
- National Institutes of Health
Methods of preparing fluorinated retinoids with labels located on odd-numbered carbons as well on even-numbered carbons and those containing trifluoromethyl groups are reviewed. The use of such retinoids in studies of protein-bound species is summarized, including the application of F-19 NMR spectroscopy for elucidating the mechanism of cis/trans isomerization, restricted rotation within the protein binding pocket, and identification of specific protein substrate interactions. The fluorine label was also useful for wavelength attenuation of protein-bound species (including formation of NIR absorbing pigments) and for other unique. applications. The more limited studies available on fluorinated carotenoids are also reviewed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据