期刊
JOURNAL OF NATURAL PRODUCTS
卷 73, 期 8, 页码 1448-1452出版社
AMER CHEMICAL SOC
DOI: 10.1021/np100325q
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资金
- MIUR
- University of Camerino
- WHO
- EU [223736]
- European Community [IP-018834]
Eight known and two new triterpenoid derivatives, neemfruitins A (9) and B (10), have been isolated from the fruits of neem, Azadirachta indica, a traditional antimalarial plant used by Asian and African populations. In vitro antiplasmodial tests evidenced a significant activity of the known gedunin and azadirone and the new neemfruitin A and provided useful information about the structure antimalarial activity relationships in the limonoid class.
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