期刊
JOURNAL OF NATURAL PRODUCTS
卷 73, 期 2, 页码 167-171出版社
AMER CHEMICAL SOC
DOI: 10.1021/np900538r
关键词
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资金
- Guangzhou Municipal Science and Technology Commission [2004Z1-E5011]
Four new bis-beta-carboline alkaloids, quassidines A-D (1-4), together with a known alkaloid, picrasidine C (5), were isolated from the sterns of Picrasma quassioides. Quassidine A (1) is the first reported bis-beta-carboline alkaloid possessing a novel cyclobutane moiety. The structures of the new compounds were determined oil the basis of their 1D and 2D NMR and X-ray diffraction data. A possible biogenetic pathway for these alkaloids was proposed, and all compounds were evaluated for anti-inflammatory activity. Only quassidine A (1) showed weak activity.
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