期刊
JOURNAL OF NATURAL PRODUCTS
卷 71, 期 4, 页码 525-531出版社
AMER CHEMICAL SOC
DOI: 10.1021/np070283+
关键词
-
Two novel triterpene holostane glycosides, synaptosides A (1) and A(1) (2), have been isolated from the Vietnamese sea cucumber Synapta maculata (Synaptida, Apodida). Their structures were elucidated by spectroscopic methods (NMR and MS) and chemical transformations. Glycosides I and 2 have rare branched pentasaccharide carbohydrate chains featuring a 3-O-methylglucuronic acid residue not previously reported in glycosides from sea cucumbers and a 6-O-sulfated glucose. Glycoside 2 has an oxo group at C-7 and a 8(9)-double bond. All these structural features are unknown in glycosides from sea cucumbers. Glycoside I has moderate cytotoxic activity (IC50 8.6 mu g/mL) and glycoside 2 is inactive against HeLa tumor cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据