Lignans from Kadsura angustifolia

Phytochemical investigation of Kadsura angustifolia led to the isolation and identification of 26 lignans and two triterpenoids, including I I new lignans named kadangustins A-K (1-11). The structures and stereochemistry of 1-11 were elucidated by. analysis of spectroscopic data. Except for 11 and 20, all the lignans were evaluated for their inhibitory activity against HIV-1. Binankadsurin A (19) showed anti-HIV activity with an EC50 value of 3.86 mu M.