期刊
JOURNAL OF NATURAL PRODUCTS
卷 71, 期 8, 页码 1458-1460出版社
AMER CHEMICAL SOC
DOI: 10.1021/np800107c
关键词
-
资金
- Ministry of Land, Transport and Maritime Affairs, Republic of Korea
Chlorohydroaspyrones A (1) and B (2), antibacterial aspyrone derivatives, and the previously described aspyrone (3), asperlactone (4), and penicillic acid (5) have been isolated from the broth of a marine isolate of the fungus Evophiala. The structure and absolute stereochemistry of the Compounds were determined on the basis of the physicochemical data analysis and chemical reactions. Compounds I and 2 exhibited a mild antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus, and multidrug-resistant S. aureus. The MIC values of each strain are as follows: compound 1 showed 62.5 mu g/mL for S. aureus and 125 mu g/mL for methicillin-resistant S. aureus and multidrug-resistant S. aureus. and compound 2, 62.5 mu g/mL for S. aureus and methicillin-resistant S. aureus and 125 mu g/mL for multidrug-resistant S. aureus.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据