4.4 Article

Antioxidative flavonol glycosides from the flowers of Abelmouschus manihot

期刊

JOURNAL OF NATURAL MEDICINES
卷 67, 期 1, 页码 78-85

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SPRINGER JAPAN KK
DOI: 10.1007/s11418-012-0651-1

关键词

Abelmouschus manihot; Flavonol glycosides; Antioxidative activity; Aldose reductase inhibitor; DPPH scavenging activity

资金

  1. Program for Changjiang Scholars and Innovative Research Team in University [PCSIR IRT0973]
  2. Applied Basic and Advanced Research Program of Tianjin [10SYSYJC28900, 10ZCKFSY09300]
  3. Ministry of Science and Technology of China [2012ZX09103201-031]

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Bioassay-guided fractionation led to the isolation of six new flavonol glycosides, floramanosides A (1), B (2), C (3), D (4), E (5), and F (6), from the flowers of Abelmouschus manihot. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D- and 2D-NMR). Activity screening results showed that the compounds had 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities.

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