4.4 Article

Lignan and neolignan glucosides, and tachioside 2'-O-4aEuro3-O-methylgallate from the leaves of Glochidion rubrum

期刊

JOURNAL OF NATURAL MEDICINES
卷 63, 期 4, 页码 408-414

出版社

SPRINGER TOKYO
DOI: 10.1007/s11418-009-0344-6

关键词

Glochidion rubrum; Euphorbiaceae; Lignan glucoside; Neolignan glucoside; Tachioside 2 '-O-4 ''-methylgallate

资金

  1. Ministry of Education, Science, Sports, Culture and Technology of Japan
  2. Japan Society for the Promotion of Science
  3. Ministry of Health, Labour and Welfare
  4. Astellas Foundation for Research on Medicinal Resources
  5. Takeda Science Foundation

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Thirteen compounds (1-13) were isolated from a MeOH extract of leaves of Glochidion rubrum. The structures of four new compounds were elucidated to be (-)-isolariciresinol 2a-O-beta-d-glucopyranoside (1), (7R,8S)- and (7R,8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignan 7-O-beta-d-glucopyranosides (2 and 3, respectively), and tachioside 2'-O-4aEuro(3)-O-methylgallate (4) on detailed inspection of one- and two-dimensional NMR spectral data.

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