期刊
JOURNAL OF NATURAL MEDICINES
卷 63, 期 3, 页码 355-359出版社
SPRINGER JAPAN KK
DOI: 10.1007/s11418-009-0331-y
关键词
Piperaceae; Betel; Piper betle; Hydroxychavicol; Allopurinol; Eugenol
资金
- Ministry of Education, Culture, Sports, Science and Technology
The screening of Piperaceous plants for xanthine oxidase inhibitory activity revealed that the extract of the leaves of Piper betle possesses potent activity. Activity-guided purification led us to obtain hydroxychavicol as an active principle. Hydroxychavicol is a more potent xanthine oxidase inhibitor than allopurinol, which is clinically used for the treatment of hyperuricemia.
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