期刊
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷 13, 期 6, 页码 4330-4333出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2013.6904
关键词
FRET-Based Nanoprobe; CdTe QD; Rhodamine B; Gelatin Nanoparticle
类别
资金
- National Natural Science Foundation of China [30873197]
- Graduate Innovation Foundation of Jiangsu Province [CXLX11_0792)]
- Graduate Innovation Foundation of Simcere Pharmaceutical Group [02704042]
A FRET-based nanoprobe consisting of CdTe quantum dot as donor and rhodamine B as acceptor embedded in gelatin nanoparticles was constructed and the photophysics of the system was characterized. The FRET-based sensors were led to at fixed donor/acceptor distance by synthesizing via a two-step desolvation way. This approach allowed for short acceptor donor separation and thus for high energy transfer efficiencies. The morphology of the nanoprobes was presented spherically and relatively uniform with a diameter of about 100 nm, which was characterized by transmission electron microscope. The luminescent property was proved to be stable in vitro and in living cells, indicating that the nanoprobes can be expected to be promising candidates for biological imaging studies.
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