4.4 Article

Superparamagnetic nanotraps containing MIP based mimic lipase for biotransformations uses

期刊

JOURNAL OF NANOPARTICLE RESEARCH
卷 13, 期 5, 页码 2073-2079

出版社

SPRINGER
DOI: 10.1007/s11051-010-9962-x

关键词

Biotransformations; Molecularly imprinted polymer (MIP); Nanotraps; Lipase; Nanobiotechnology

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The nanoparticle comprises a superparamagnetic iron oxide nanoparticle core conjugated with trimethoxylsilyl propylmethacrylate (TMSPM) and methacryloylamido serine (MASE), methacryloylamido histidine (MAH), methacryloylamido glutamic acid (MAGA) monomers, and p-nitrophenyl palmitate (p-NPP) which is a substrate of lipase as a template molecule, which enables the creation of lipase active region. The resulting hybrid superparamagnetic nanotraps are magnetically separable, highly active, and stable under harsh conditions. In this study, the advantages of high selectivity of molecular imprinting technique have used to get mimic lipase for the synthesis of methyl jasmonate and methyl oleate.

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