期刊
JOURNAL OF NANOMATERIALS
卷 2013, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2013/893970
关键词
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资金
- Ministry of Educations of the Romania under Program CEA-IFA [C2-06, POSDRU/107/1.5/S/76813]
- (AntiBioTube) program [94/PN2/PCCA]
- French government via the cultural section of the French Embassy
The aim of this study was to provide information about the biological properties of iron oxide nanoparticles (IO-NPs) obtained in an aqueous suspension. The IO-NPs were characterized by transmission electron microscopy (TEM). Analysis of hysteresis loops data at room temperature for magnetic IO-NPs sample indicated that the IO-NPs were superparamagnetic at room temperature. The calculated saturation magnetization for magnetic iron oxide was M-s = 18.1 emu/g. The antimicrobial activity of the obtained PMC-NPs was tested against Gram-negative (Pseudomonas aeruginosa 1397, Escherichia coli ATCC 25922), Gram-positive (Enterococcus faecalis ATCC 29212, Bacillus subtilis IC 12488) bacterial as well as fungal (Candida krusei 963) strains. The obtained results suggested that the antimicrobial activity of IO-NPs is dependent on the metallic ions concentrations and on the microbial growth state, either planktonic or adherent. The obtained IO-NPs exhibited no cytotoxic effect on HeLa cells at the active antimicrobial concentrations.
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