期刊
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
卷 34, 期 3-4, 页码 261-274出版社
SPRINGER
DOI: 10.1007/s10974-013-9355-8
关键词
Tropomyosin; Cytoskeleton; Actin; Cytoskeletal regulation
类别
资金
- Kids Cancer Project
- National Health and Medical Research Council (NHMRC) [APP1004188]
- Australian Postgraduate Award
The actin cytoskeleton plays a central role in many essential cellular processes. Its involvement requires actin filaments to form multiple populations with different structural and therefore functional properties in specific subcellular locations. This diversity is facilitated through the interaction between actin and a number of actin binding proteins. One family of proteins, the tropomyosins, are absolutely essential in regulating actin's ability to form such diverse structures. In this review we integrate studies from different organisms and cell types in an attempt to provide a unifying view of tropomyosin dependent regulation of the actin cytoskeleton.
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