期刊
JOURNAL OF MOLECULAR STRUCTURE
卷 1061, 期 -, 页码 76-81出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molstruc.2013.12.067
关键词
Phenoxyacetic acid herbicides; MCPA; beta-Cyclodextrin; Inclusion complex
资金
- Fundacao para a Ciencia e Tecnologia FCT/MCTES [PTDC/AGRAAM/105044/2008]
- European Community Fund FEDER through COMPETE - Programa Operacional Factores de Competitividade (POFC)
- FCT [SFRH/BPD/ 74491/2010]
- Portuguese Fundacao para a Ciencia e a Tecnologia through the program Ciencia [PEst-OE/EEI/UI0752/2011]
- SeARCH (Services and Advanced Research Computing with HTC/HPC clusters) [CONC-REEQ/443/2005]
- Fundação para a Ciência e a Tecnologia [PEst-OE/EEI/UI0752/2011] Funding Source: FCT
When a pesticide is released into the environment, most of it is lost before it reaches its target. An effective way to reduce environmental losses of pesticides is by using controlled release technology. Microencapsulation becomes a promising technique for the production of controlled release agricultural formulations. In this work, the microencapsulation of chlorophenoxy herbicide MCPA with native beta-cyclodextrin and its methyl and hydroxypropyl derivatives was investigated. The phase solubility study showed that both native and beta-CD derivatives increased the water solubility of the herbicide and inclusion complexes are formed in a stoichiometric ratio of 1:1. The stability constants describing the extent of formation of the complexes have been determined by phase solubility studies. H-1 NMR experiments were also accomplished for the prepared solid systems and the data gathered confirm the formation of the inclusion complexes. H-1 NMR data obtained for the MCPA/CDs complexes disclosed noticeable proton shift displacements for OCH2 group and H6 aromatic proton of MCPA provided clear evidence of inclusion complexation process, suggesting that the phenyl moiety of the herbicide was included in the hydrophobic cavity of CDs. Free energy molecular mechanics calculations confirm all these findings. The gathered results can be regarded as an essential step to the development of controlled release agricultural formulations containing herbicide MCPA. (C) 2014 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据