期刊
JOURNAL OF MOLECULAR STRUCTURE
卷 1006, 期 1-3, 页码 318-323出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molstruc.2011.09.026
关键词
4b,9b-Dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione; Inter-molecular hydrogen bonding; Crystal structure; NMR spectra; Antimicrobial activity; Cholinesterase enzymes
资金
- Universiti Sains Malaysia (USM) [1001/PTEKIND/8140152]
The crystal structure of the title compound, 4b,9b-dihydroxy-7,8-dihydro-4bH-indeno[1,2-b]benzofuran-9,10(6H,9bH)-dione has been determined by single crystal X-ray diffraction. It crystallizes in the monoclinic space group P2(1)/c with Z = 4. The FTIR as well as the H-1 and C-13 NMR spectra of the compound were also recorded and briefly discussed. The compound showed potential antimicrobial activity comparable to that of clinically used antimicrobial agents against selected microorganisms. It has selective and moderate inhibitory activity on butyryl cholinesterase enzyme and could serve as potential lead compound for synthesis of more bioactive derivatives. (C) 2011 Elsevier B.V. All rights reserved.
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