期刊
JOURNAL OF MOLECULAR MEDICINE-JMM
卷 87, 期 11, 页码 1053-1060出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00109-009-0520-x
关键词
ATF3; Transcriptional regulation; Immunity; TLRs; Oncogenesis; Gene expression
资金
- National Institutes of Health [P01 CA062220]
- Australian Rotary Health Research Fund
Activating transcription factor 3 (ATF3) is a member of the ATF/cyclic AMP response element-binding (ATF/CREB) family of transcription factors. It is an adaptive-response gene that participates in cellular processes to adapt to extra- and/or intracellular changes, where it transduces signals from various receptors to activate or repress gene expression. Advances made in understanding the immunobiology of Toll-like receptors have recently generated new momentum for the study of ATF3 in immunity. Moreover, the role of ATF3 in the regulation of the cell cycle and apoptosis has important implications for understanding susceptibility to and progression of several cancers.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据