期刊
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
卷 76, 期 -, 页码 89-93出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.molcatb.2011.11.013
关键词
Efflux pump; AcrAB-ToIC; Alcohol tolerance
资金
- A*STAR in Singapore [ICES/07-173B01]
We investigated the alcohol tolerance of Escherichia coli acrR and marR regulatory mutants. The local repressor gene acrR and the global repressor gene marR were deleted either separately or together from the genomic DNA of E. coli for overexpression of AcrAB-ToIC. Mutants with Delta acrR background indicated no growth difference in the exponential growth phase and modestly better growth in the stationary growth phase than the parental strain under various concentrations of alcohol. However, single marR mutant did not show any better growth than the parental strain in the presence of butanol and isobutanol although the efflux pump AcrAB-ToIC was upregulated. (C) 2011 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据