Enantioselective acetylation of racemic alcohols by Manihot esculenta and Passiflora edulis preparations

Immobilized Manihot esculenta and Passiflora edulis juice preparations have been employed as stereoselective biocatalysts in the enzymatic acetylation of a set of racemic alcohols. Depending on the reaction conditions and the substrate Structure, good to excellent enantioselectivities can be achieved in the preparation of the (S)-alcohols and (R)-esters, compounds presenting high interest in organic synthesis. (C) 2009 Elsevier B.V. All rights reserved.