A simple, efficient and recyclable phosphine-free catalytic system for Suzuki-Miyaura reaction of aryl bromides

The Suzuki-Miyaura reaction of aryl bromides using 3-(2-aminoethylamino)propyl-functionalized MCM-41-immobilized palladium(II) complex [MCM-41-2N-Pd(II)] as an efficient heterogeneous catalyst is described. Developed catalytic system is found to be effective for the Suzuki-Miyaura reaction of aryl bromides with arylboronic acids providing good to excellent yield of the desired products. This heterogeneous palladium catalyst can be reused at least 10 times without any decrease in activity. Our system not only avoids the use of phosphine ligands, but also solves the basic problem of palladium catalyst recovery and reuse. (C) 2011 Elsevier B.V. All rights reserved.