期刊
JOURNAL OF MOLECULAR BIOLOGY
卷 430, 期 20, 页码 3642-3656出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jmb.2018.07.026
关键词
functional amyloid fibers; biofilm matrix; curli; TasA; PSM
资金
- Biotechnology and Biological Sciences Research Council [BB/P001335/1, BB/R012415/1, BB/N022254/1]
- Wellcome Institutional Strategic Support Fund [097818/Z/11]
- BBSRC [BB/P001335/1, BB/N022254/1, BB/R012415/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/R012415/1] Funding Source: researchfish
Biofilms are ubiquitous in the natural and man-made environment. They are defined as microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing evidence from the genetic and biochemical analysis of single species biofilms has linked the presence of fibrous proteins to a functional biofilm matrix. Some of these fibers have been described as functional amyloid or amyloid-like fibers. Here we provide an overview of the biophysical and biological data for a wide range of protein fibers found in the biofilm matrix of Gram-positive and Gram-negative bacteria. (C) 2018 The Authors. Published by Elsevier Ltd.
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