期刊
JOURNAL OF MEDICINAL CHEMISTRY
卷 53, 期 7, 页码 2779-2796出版社
AMER CHEMICAL SOC
DOI: 10.1021/jm901488g
关键词
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资金
- CaPCURE
- Prostate Cancer Foundation
- NIH [5P50CA-92131]
A structure activity relationship study was carried out on a series of thiohydantoins and their analogues 14 which led to the discovery of 92 (MDV3100) as the clinical candidate for the treatment of hormone refractory prostate cancer.
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