期刊
JOURNAL OF MEDICAL VIROLOGY
卷 84, 期 8, 页码 1208-1216出版社
WILEY-BLACKWELL
DOI: 10.1002/jmv.23323
关键词
treatment; ribavirin; IL28B polymorphism; pegylated interferon-a
类别
IL28B genotypes and virological response within 4 weeks are predictors of sustained virological response in patients infected with chronic hepatitis C virus (HCV) genotype 1 treated with antiviral dual combination therapy. The predictive value of early anemia (within 4 weeks) alone or in combination with the two other predictors has not been studied yet. A total of 305 pegylated interferon-a and ribavirin-treated patients with HCV genotype 1 were included in this study. Hemoglobin values at week 0, 4, 8, and 12 as well as the predictive efficiency of early anemia (hemoglobin value below the gender-specific lower limit: female?
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