期刊
JOURNAL OF MEDICAL PRIMATOLOGY
卷 41, 期 4, 页码 266-277出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1600-0684.2012.00547.x
关键词
air sac; air sacculitis; non-human primate; pan; papio
资金
- NCRR [P51 RR013986]
Background Air sacculitis is an important clinical condition in non-human primates. Methods We evaluated 37 baboons and seven chimpanzees with spontaneous air sacculitis submitted to pathology over a 20-year period. Results Air sacculitis was observed almost exclusively in males. Common reported signs were halitosis, coughing, nasal discharges, depression, anorexia, and weight loss. Gross lesions included thickened air sacs and suppurative exudate lining the walls. Microscopic lesions included marked epithelial hyperplasia or hypertrophy, necrosis, fibrosis, cellular infiltrates, and bacterial colonies. Mixed bacterial infections were more common than infections by single species of bacteria. Streptococcus sp. was the most frequent bacteria isolated in both baboons and chimpanzees. Conclusions This is the first report describing the gross and microscopic lesions of air sacculitis in chimpanzees. The preponderance of males suggests a male sex predilection in baboons.
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