期刊
JOURNAL OF MEDICAL PRIMATOLOGY
卷 38, 期 1, 页码 70-73出版社
WILEY
DOI: 10.1111/j.1600-0684.2008.00314.x
关键词
brucella; non-human primates; stillbirth
资金
- UK Department of Environment, Food and Rural Affairs (Defra)
- NIH [P51 RR013986, C06 RR15456]
Brucellosis is veterinary and human health problem. A 13-year-old wild caught multiparous and an 8-year-old colony-born nulliparous baboon had stillbirths in the second trimester of pregnancy. Culture isolates from both postpartum uteruses were characterized using traditional biochemical analysis, PCR, and multilocus sequencing. The isolates morphologically resembled Brucella although their phenotypic characteristics were not consistent with any currently described species. The isolates represent a novel lineage within the genus with unique alleles, not previously seen in surveys of greater than 300 isolates representing the known diversity of the genus, present at 5/9 loci examined. The described cases are to the best of our knowledge the first presentation of a naturally acquired Brucella infection in non-human primates associated with stillbirths from the same colony where Brucella seropositivity in the baboons was described 45 years ago. The organism appears to represent a previously undescribed Brucella species.
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