期刊
JOURNAL OF MEDICAL INTERNET RESEARCH
卷 12, 期 5, 页码 -出版社
JOURNAL MEDICAL INTERNET RESEARCH
DOI: 10.2196/jmir.1436
关键词
Costs and cost analysis; cost-benefit analysis; depression; Internet; computer-assisted instruction; cognitive therapy; problem solving; randomized controlled trial
资金
- Faculty of Psychology and Education at the VU University, Amsterdam
Background: The effectiveness of Internet-based treatments for depression has been demonstrated; their cost-effectiveness, however, has been less well researched. Objective: Evaluating the relative cost-utility and cost-effectiveness of (1) Internet-based cognitive behavioral therapy, (2) Internet-based problem-solving therapy, and (3) a waiting list for adults with depressive symptoms. Methods: A total of 263 participants with clinically significant depressive symptoms were randomized to Internet-based cognitive behavioral therapy (n = 88), Internet-based problem-solving therapy (n = 88), and a waiting list (n = 87). End points were evaluated at the 12-week follow-up. Results: Cost-utility analysis showed that cognitive behavioral therapy and problem-solving therapy had a 52% and 61% probability respectively of being more acceptable than waiting when the willingness to pay is (sic) 30,000 for one quality-adjusted life-year. When society is prepared to pay (sic) 10,000 for a clinically significant change from depression, the probabilities of cognitive behavioral therapy and problem-solving therapy being more acceptable than waiting are 91% and 89%, respectively. Comparing both Internet-based treatments showed no clear preference for one or the other of the treatments. Conclusions: Both Internet-based treatments have a high probability of being cost-effective with a modest value placed on clinically significant change in depressive symptoms.
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