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Long-Term Results of Balloon Valvuloplasty as Primary Treatment for Congenital Aortic Valve Stenosis: a 20-Year Review

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PEDIATRIC CARDIOLOGY
卷 36, 期 6, 页码 1145-1152

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SPRINGER
DOI: 10.1007/s00246-015-1134-4

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Congenital valvular aortic stenosis; Balloon valvuloplasty; Outcome; Shone's syndrome

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In the presence of new surgical techniques, the treatment of congenital valvular aortic stenosis is under debate. We reviewed the results and late outcomes of all 93 patients aged 1 day to 18 years, treated with balloon valvuloplasty (BAV) as first-line therapy for congenital aortic valve stenosis in our center from January 1991 to May 2012. Mean age at procedure time was 2.4 years; 37 patients underwent BAV at age a parts per thousand currency sign30 days (neonates), 29 patients at age a parts per thousand yen1 month and < 1 year (infants), and 27 patients were older than 1 year (children). The invasive BAV peak-to-peak aortic valve gradient (mean 59 +/- A 22 mmHg) was immediately reduced (mean 24 +/- A 12 mmHg). The observed diminution of gradient was similar for each age group. Four patients had significant post-BAV AI. Mean follow-up after BAV was 11.4 +/- A 7 years. The last echo peak aortic gradient was 37 +/- A 18 mmHg and mean gradient was 23 +/- A 10 mmHg, and two patients had significant AI. Actuarial survival for the whole cohort was 88.2 and 72.9 % for the neonates. All infants, except one, and all children survived. Sixty-six percent of patients were free from surgery, and 58 % were free from any reintervention, with no difference according to age. Freedom from surgery after BAV at 5, 10, and 20 years, respectively, was 82, 72, and 66 %. Our study confirms that BAV as primary treatment for congenital AS is an efficient and low-risk procedure in infants and children. In neonates, the prognosis is more severe and clearly related to borderline LV..

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