期刊
PEDIATRIC BLOOD & CANCER
卷 62, 期 8, 页码 1305-1316出版社
WILEY
DOI: 10.1002/pbc.25501
关键词
diagnosis; low income countries; MYCN; Neuroblastoma; resource limited countries; treatment
资金
- Mildred V. Strouss chair
- Dougherty Foundation
- Campini Foundation
- Conner fund
- American Lebanese Syrian Associated Charities (ALSAC)
- Fondazione Umberto Veronesi
Neuroblastoma is the most common extracranial solid tumor in childhood in high-income countries (HIC), where consistent treatment approaches based on clinical and tumor biological risk stratification have steadily improved outcomes. However, in low- and middle- income countries (LMIC), suboptimal diagnosis, risk stratification, and treatment may occur due to limited resources and unavailable infrastructure. The clinical practice guidelines outlined in this manuscript are based on current published evidence and expert opinions. Standard risk stratification and treatment explicitly adapted to graduated resource settings can improve outcomes for children with neuroblastoma by reducing preventable toxic death and relapse. Pediatr Blood Cancer 2015;62:1305-1316. (c) 2015 The Authors. Pediatric Blood & Cancer, published by Wiley Periodicals, Inc.
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