期刊
JOURNAL OF MATHEMATICAL BIOLOGY
卷 58, 期 1-2, 页码 285-322出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00285-008-0165-3
关键词
Dynamical hematological diseases; Mathematical modeling
We review the basic characteristics of four periodic hematological disorders (periodic auto-immune hemolytic anemia, cyclical thrombocytopenia, cyclical neutropenia and periodic chronic myelogenous leukemia) and examine the role that mathematical modeling and numerical simulations have played in our understanding of the origin of these diseases and in the regulation of hematopoiesis.
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