期刊
JOURNAL OF MATERIALS RESEARCH
卷 28, 期 2, 页码 185-192出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1557/jmr.2012.265
关键词
-
资金
- Robert A. Welch Foundation [P-1212]
In this study, silicon nanowire (SiNW)/polycaprolactone composites with different surface topographies were fabricated by straightforward embedding or printing methods and their cytocompatibility was evaluated with a bone-relevant cell line derived from mouse stroma. The incorporation of biocompatible polymers with semiconducting SiNWs can ideally provide an enhanced environment to support proliferation and differentiation functions of bone cells. Cell/composite interactions were assessed with suitable assays including viability and alkaline phosphatase activity, while scanning electron microscopy characterization was used to study the morphology of cells grown on composites. Such results suggest that for nanowires in a vertical array, the presence of the polymer improves cellular attachment and overall viability relative to the nanowire-only system.
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