期刊
JOURNAL OF MATERIALS CHEMISTRY
卷 22, 期 2, 页码 432-439出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1jm14303d
关键词
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资金
- Central Laser Facility, STFC Rutherford Appleton Laboratory [App101002]
- Science Foundation Ireland [10/RFP/CAP2915]
- EPA Ireland [2008-PhD-WRM-2]
- Environmental Protection Agency Ireland (EPA) [2008-PhD-WRM-2] Funding Source: Environmental Protection Agency Ireland (EPA)
- Science Foundation Ireland (SFI) [10/RFP/CAP2915] Funding Source: Science Foundation Ireland (SFI)
Carbon based materials are attractive for biological applications because of their excellent biocompatibility profile. Porous carbons with high specific surface area are particularly interesting because it is possible in principle to leverage their properties to deliver high drug payloads. In this work, porous carbon microspheres with high specific surface area were prepared and studied in solution and in cells. Raman optical tweezer trapping of microspheres, excited at 532 nm, results in graphitization and incandescence in solvents that display poor heat conduction. Fluorescence confocal microscopy imaging was used to demonstrate the uptake of fluorescently labelled microspheres by cells and the ability to leverage their optical absorptivity in order to cause carbon graphitization and cell death.
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