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BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9

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JOURNAL OF MATERIALS CHEMISTRY
卷 21, 期 14, 页码 5219-5222

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c1jm10199d

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For the first time, we demonstrated BN nanospheres (BNNSs) can interact with biomolecules and deliver unmethylated cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) into cells to activate toll-like receptor 9 (TLR9), which is a very important process for therapy of cancers and allergy diseases.

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