期刊
JOURNAL OF MATERIALS CHEMISTRY
卷 21, 期 26, 页码 9467-9470出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1jm11150g
关键词
-
资金
- 21C Frontier Functional Proteomics Project [FPR08-A2-150]
- Korea Science and Engineering Foundation [2008-02890]
- Ministry of Education, Science and Technology [2009-0077361]
- Ministry of Knowledge Economy [10033183]
We synthesized highly stable, amphiphilic polymer-protected DNA-Au nanoparticle conjugates (DNA-AuNPs) and developed a DNA encoding/decoding strategy using these particles. Here, DNA-AuNPs were encapsulated by amphiphilic poly(N-vinyl-2-pyrrolidone) (PVP) to make them more stable and soluble in both organic and aqueous solvents. These particles are stable in a wide range of salt concentrations, pH and temperatures and sustain their stability even after the addition of D, L-dithiothreitol. Finally, this polymer layer was readily removed and particle-modified DNA was decoded via the microarrayed chip and dark-field-based AuNP imaging technique.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据